49ers 5 keys to winning at Tampa Bay, improving to 4-0 on road

Published: Saturday, October 11, 2025 at 11:30 am

49ers Seek Road Victory Against Buccaneers

The San Francisco 49ers are heading into a crucial matchup against the Tampa Bay Buccaneers, aiming to extend their road record to 4-0. The Buccaneers have a knack for late-game heroics, with all four of their wins this season coming in come-from-behind fashion. The 49ers, known for their own ability to win close games, are prepared for a tough battle.

One key factor for the 49ers will be containing Buccaneers quarterback Baker Mayfield, who has yet to defeat the 49ers in his career. The 49ers defense, led by linebacker Fred Warner, will be tasked with disrupting Mayfield's rhythm. Warner, a key player for the 49ers, is nearing a franchise record for tackles.

Offensively, the 49ers will rely on running back Christian McCaffrey, despite his recent lack of rushing touchdowns. McCaffrey remains a significant threat in the passing game. The 49ers will also need to capitalize on the Buccaneers' defensive vulnerabilities, particularly in the secondary, where injuries have created opportunities.

The 49ers' backup quarterback, Mac Jones, is expected to start, and the team will need to overcome injuries to key receivers. The Buccaneers' rookie wide receiver, Emeka Egbuka, has emerged as a significant threat, posing a challenge for the 49ers' defense.

BNN's Perspective: This game promises to be a hard-fought contest between two teams with a penchant for close finishes. While the 49ers are favored, the Buccaneers' ability to rally late in games makes them a dangerous opponent. The outcome will likely hinge on which team can execute its game plan most effectively and capitalize on its opportunities.

Keywords: 49ers, Buccaneers, Baker Mayfield, Fred Warner, Christian McCaffrey, Emeka Egbuka, NFL, football, road game, Mac Jones, defense, offense, injuries, game.

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